MRTFA Mouse Monoclonal Antibody [Clone ID: LBI2B3]

Product Specifications

Background

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Overview

Carrier-free (BSA/glycerol-free) MKL1 mouse monoclonal antibody, clone LBI2B3

Synonyms

BSAC; MAL; MRTF-A

Gene Name

Homo sapiens myocardin related transcription factor A (MRTFA), transcript variant 1, mRNA.

Gene ID

57591

UniProt

Q969V6

Conjugation

Unconjugated

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Transcription Factors

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.