SAE1 Mouse Monoclonal Antibody [Clone ID: LBI6B11]
Product Specifications
Background
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) . [supplied by OMIM, Mar 2010]
Synonyms
AOS1; HSPC140; SUA1; UBLE1A
Gene Name
Homo sapiens SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1, mRNA.
Gene ID
10055
UniProt
Q9UBE0
Conjugation
Unconjugated
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Dilution
WB 1:2000, IHC 1:150
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SAE1
Overview
Carrier-free (BSA/glycerol-free) SAE1 mouse monoclonal antibody, clone LBI6B11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10055
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBE0
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