SAE1 Mouse Monoclonal Antibody [Clone ID: LBI6B11]

Product Specifications

Background

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) . [supplied by OMIM, Mar 2010]

Overview

Carrier-free (BSA/glycerol-free) SAE1 mouse monoclonal antibody, clone LBI6B11

Synonyms

AOS1; HSPC140; SUA1; UBLE1A

Gene Name

Homo sapiens SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1, mRNA.

Gene ID

10055

UniProt

Q9UBE0

Conjugation

Unconjugated

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Dilution

WB 1:2000, IHC 1:150

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.