PTCH2 Mouse Monoclonal Antibody [Clone ID: LBI1F5]
Product Specifications
Background
This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
Synonyms
PTC2
Gene Name
Homo sapiens patched 2 (PTCH2), transcript variant 1, mRNA.
Gene ID
8643
UniProt
Q9Y6C5
Conjugation
Unconjugated
Related Pathways
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
Field of Research
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PTCH2
Overview
Carrier-free (BSA/glycerol-free) PTCH2 mouse monoclonal antibody, clone LBI1F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8643
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y6C5
Curated Selection
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