XRCC3 Mouse Monoclonal Antibody [Clone ID: LBI1C1]

Product Specifications

Background

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Overview

Carrier-free (BSA/glycerol-free) XRCC3 mouse monoclonal antibody, clone LBI1C1

Synonyms

CMM6

Gene Name

Homo sapiens X-ray repair cross complementing 3 (XRCC3), transcript variant 2, mRNA.

Gene ID

7517

UniProt

O43542

Conjugation

Unconjugated

Related Pathways

Homologous recombination

Field of Research

Homologous recombination

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.