XRCC3 Mouse Monoclonal Antibody [Clone ID: LBI1C1]
Product Specifications
Background
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Synonyms
CMM6
Gene Name
Homo sapiens X-ray repair cross complementing 3 (XRCC3), transcript variant 2, mRNA.
Gene ID
7517
UniProt
O43542
Conjugation
Unconjugated
Related Pathways
Homologous recombination
Field of Research
Homologous recombination
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
XRCC3
Overview
Carrier-free (BSA/glycerol-free) XRCC3 mouse monoclonal antibody, clone LBI1C1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7517
Uniprot URL
https://www.uniprot.org/uniprot/O43542
Curated Selection
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