NIPP1 (PPP1R8) Mouse Monoclonal Antibody [Clone ID: LBI1E2]
Product Specifications
Background
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul
Synonyms
ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
Gene Name
Homo sapiens protein phosphatase 1 regulatory subunit 8 (PPP1R8), transcript variant 2, mRNA.
Gene ID
5511
UniProt
Q12972
Conjugation
Unconjugated
Dilution
WB 1:2000
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Transcription Factors
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PPP1R8
Overview
Carrier-free (BSA/glycerol-free) PPP1R8 mouse monoclonal antibody, clone LBI1E2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5511
Uniprot URL
https://www.uniprot.org/uniprot/Q12972
Curated Selection
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