APPBP1 (NAE1) Mouse Monoclonal Antibody [Clone ID: LBI1E9]
Product Specifications
Background
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
A-116A10.1; APPBP1; HPP1; ula-1
Gene Name
Homo sapiens NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 3, mRNA.
Gene ID
8883
UniProt
Q13564
Conjugation
Unconjugated
Related Pathways
Alzheimer's disease
Field of Research
Alzheimer's disease
Dilution
WB 1:500
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NAE1
Overview
Carrier-free (BSA/glycerol-free) NAE1 mouse monoclonal antibody, clone LBI1E9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8883
Uniprot URL
https://www.uniprot.org/uniprot/Q13564
Curated Selection
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