ACE2 Mouse Monoclonal Antibody [Clone ID: LBI3C2] (Angiotensin Converting Enzyme 2)
Product Specifications
Background
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008].
Synonyms
ACEH
Gene Name
Homo sapiens angiotensin converting enzyme 2 (ACE2), transcript variant 2, mRNA.
Gene ID
59272
UniProt
Q9BYF1
Conjugation
Unconjugated
Related Pathways
Renin-angiotensin system
Field of Research
Renin-angiotensin system
Form
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ACE2
Overview
Carrier-free (BSA/glycerol-free) ACE2 mouse monoclonal antibody, clone LBI3C2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=59272
Uniprot URL
https://www.uniprot.org/uniprot/Q9BYF1
Curated Selection
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