BCL2 Mouse Monoclonal Antibody [Clone ID: UMLBI225]
Product Specifications
Background
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]
Overview
BCL2 mouse monoclonal antibody, clone UMLBI225
Synonyms
Bcl-2; PPP1R50
Gene Name
Homo sapiens BCL2 apoptosis regulator (BCL2), transcript variant alpha, mRNA.
Gene ID
596
UniProt
P10415
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer
Field of Research
Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BCL2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=596
Uniprot URL
https://www.uniprot.org/uniprot/P10415
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