Cardiac Troponin T (TNNT2) Mouse Monoclonal Antibody [Clone ID: UMLBI205]
Selected Variant
AMM21941V
Size: 100 µL
Product Specifications
Background
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. (provided by RefSeq, Jul 2008)
Overview
Troponin T (TNNT2) mouse monoclonal antibody, clone UMLBI205
Synonyms
CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Gene Name
Homo sapiens troponin T2, cardiac type (TNNT2), transcript variant 1, mRNA.
Gene ID
7139
UniProt
P45379
Conjugation
Unconjugated
Related Pathways
Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Field of Research
Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
IHC 1:100~200
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNNT2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7139
Uniprot URL
https://www.uniprot.org/uniprot/P45379
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