PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: UMLBI199]
Product Specifications
Background
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul
Synonyms
CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Gene Name
Homo sapiens programmed cell death 1 (PDCD1), mRNA.
Gene ID
5133
UniProt
Q15116
Conjugation
Unconjugated
Related Pathways
Cell adhesion molecules (CAMs), T cell receptor signaling pathway
Field of Research
Cell adhesion molecules (CAMs), T cell receptor signaling pathway
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
IHC 1:1000, WB 1:500, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDCD1
Overview
PD-1 (PDCD1) mouse monoclonal antibody, clone UMLBI199
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5133
Uniprot URL
https://www.uniprot.org/uniprot/Q15116
Curated Selection
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