PD1 (PDCD1) Mouse Monoclonal Antibody [Clone ID: UMLBI199]

Product Specifications

Background

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul

Overview

PD-1 (PDCD1) mouse monoclonal antibody, clone UMLBI199

Synonyms

CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2

Gene Name

Homo sapiens programmed cell death 1 (PDCD1), mRNA.

Gene ID

5133

UniProt

Q15116

Conjugation

Unconjugated

Related Pathways

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Field of Research

Cell adhesion molecules (CAMs), T cell receptor signaling pathway

Concentration

0.5~1.0 mg/ml (Lot Dependent)

Dilution

IHC 1:1000, WB 1:500, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.