TTF1 (NKX2-1) Mouse Monoclonal Antibody [Clone ID: UMLBI162]
Product Specifications
Background
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb
Synonyms
BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1
Gene Name
Homo sapiens NK2 homeobox 1 (NKX2-1), transcript variant 2, mRNA.
Gene ID
7080
UniProt
P43699
Conjugation
Unconjugated
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
IHC 1:200
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NKX2-1
Overview
TTF1 (NKX2-1) mouse monoclonal antibody, clone UMLBI162
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7080
Uniprot URL
https://www.uniprot.org/uniprot/P43699
Curated Selection
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