Proteasome subunit alpha type 6 (PSMA6) Mouse Monoclonal Antibody [Clone ID: UMLBI102]
Product Specifications
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]
Synonyms
IOTA; p27K; PROS27
Gene Name
Homo sapiens proteasome 20S subunit alpha 6 (PSMA6), transcript variant 1, mRNA.
Gene ID
5687
UniProt
P60900
Conjugation
Unconjugated
Related Pathways
Proteasome
Field of Research
Proteasome
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
IHC 1:100, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease, Stem cell - Pluripotency
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PSMA6
Overview
PSMA6 mouse monoclonal antibody, clone UMLBI102
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5687
Uniprot URL
https://www.uniprot.org/uniprot/P60900
Curated Selection
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