Proteasome subunit alpha type 6 (PSMA6) Mouse Monoclonal Antibody [Clone ID: UMLBI102]

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]

Overview

PSMA6 mouse monoclonal antibody, clone UMLBI102

Synonyms

IOTA; p27K; PROS27

Gene Name

Homo sapiens proteasome 20S subunit alpha 6 (PSMA6), transcript variant 1, mRNA.

Gene ID

5687

UniProt

P60900

Conjugation

Unconjugated

Related Pathways

Proteasome

Field of Research

Proteasome

Concentration

0.5~1.0 mg/ml (Lot Dependent)

Dilution

IHC 1:100, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protease, Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.