CD44 Mouse Monoclonal Antibody [Clone ID: UMLBI133]
Product Specifications
Background
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Synonyms
CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1
Gene Name
Homo sapiens CD44 molecule (Indian blood group) (CD44), transcript variant 1, mRNA.
Gene ID
960
UniProt
P16070
Conjugation
Unconjugated
Related Pathways
ECM-receptor interaction, Hematopoietic cell lineage
Field of Research
ECM-receptor interaction, Hematopoietic cell lineage
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
WB 1:4000, IHC 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD44
Overview
CD44 mouse monoclonal antibody, clone UMLBI133
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=960
Uniprot URL
https://www.uniprot.org/uniprot/P16070
Curated Selection
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