CA12 Mouse Monoclonal Antibody [Clone ID: UMLBI121]
Product Specifications
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Synonyms
CAXII; HsT18816
Gene Name
Homo sapiens carbonic anhydrase 12 (CA12), transcript variant 1, mRNA.
Gene ID
771
UniProt
O43570
Conjugation
Unconjugated
Related Pathways
Nitrogen metabolism
Field of Research
Nitrogen metabolism
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
IHC 1:100~200
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CA12
Overview
CA12 mouse monoclonal antibody, clone UMLBI121
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=771
Uniprot URL
https://www.uniprot.org/uniprot/O43570
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