CA12 Mouse Monoclonal Antibody [Clone ID: UMLBI121]

Product Specifications

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Overview

CA12 mouse monoclonal antibody, clone UMLBI121

Synonyms

CAXII; HsT18816

Gene Name

Homo sapiens carbonic anhydrase 12 (CA12), transcript variant 1, mRNA.

Gene ID

771

UniProt

O43570

Conjugation

Unconjugated

Related Pathways

Nitrogen metabolism

Field of Research

Nitrogen metabolism

Concentration

0.5~1.0 mg/ml (Lot Dependent)

Dilution

IHC 1:100~200

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.