XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: UMLBI21]

Product Specifications

Background

The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .

Overview

XPF mouse monoclonal antibody, clone UMLBI21

Synonyms

ERCC11; FANCQ; RAD1; XFEPS; XPF

Gene Name

Homo sapiens ERCC excision repair 4, endonuclease catalytic subunit (ERCC4), mRNA.

Gene ID

2072

UniProt

Q92889

Conjugation

Unconjugated

Related Pathways

Nucleotide excision repair

Field of Research

Nucleotide excision repair

Concentration

0.5~1.0 mg/ml (Lot Dependent)

Dilution

WB 1:200~500, IF 1:100, FLOW 1:100, IHC 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.