SQSTM1 Mouse Monoclonal Antibody [Clone ID: UMLBI12]
Product Specifications
Background
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
Synonyms
A170; OSIL; p60; p62; p62B; PDB3; ZIP3
Gene Name
Homo sapiens sequestosome 1 (SQSTM1), transcript variant 1, mRNA.
Gene ID
8878
UniProt
Q13501
Conjugation
Unconjugated
Concentration
0.5~1.0 mg/ml (Lot Dependent)
Dilution
WB 1:500~2000, IHC 1:150, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SQSTM1
Overview
SQSTM1 mouse monoclonal antibody, clone UMLBI12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8878
Uniprot URL
https://www.uniprot.org/uniprot/Q13501
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