SQSTM1 Mouse Monoclonal Antibody [Clone ID: UMLBI12]

Product Specifications

Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]

Overview

SQSTM1 mouse monoclonal antibody, clone UMLBI12

Synonyms

A170; OSIL; p60; p62; p62B; PDB3; ZIP3

Gene Name

Homo sapiens sequestosome 1 (SQSTM1), transcript variant 1, mRNA.

Gene ID

8878

UniProt

Q13501

Conjugation

Unconjugated

Concentration

0.5~1.0 mg/ml (Lot Dependent)

Dilution

WB 1:500~2000, IHC 1:150, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.