Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: LBI1E7]
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
Overview
NEFL mouse monoclonal antibody, clone LBI1E7
Synonyms
CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110
Gene Name
Neurofilament, light polypeptide
Gene ID
4747
UniProt
P07196
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS)
Field of Research
Amyotrophic lateral sclerosis (ALS)
Concentration
1 mg/ml
Dilution
ELISA 1:5000-10000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEFL
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4747
Uniprot URL
https://www.uniprot.org/uniprot/P07196
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