MYBPC3 Mouse Monoclonal Antibody [Clone ID: LBI1D1]
Product Specifications
Background
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
Synonyms
CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C
Gene Name
Myosin binding protein C, cardiac
Gene ID
4607
UniProt
Q14896
Conjugation
Unconjugated
Related Pathways
Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Field of Research
Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Concentration
1 mg/ml
Dilution
ELISA 1:5000-10000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MYBPC3
Overview
MYBPC3 mouse monoclonal antibody, clone LBI1D1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4607
Uniprot URL
https://www.uniprot.org/uniprot/Q14896
Curated Selection
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