MICB Mouse Monoclonal Antibody [Clone ID: LBI2H8]

Product Specifications

Background

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Overview

MICB mouse monoclonal antibody, clone LBI2H8

Synonyms

PERB11.2

Gene Name

MHC class I polypeptide-related sequence B

Gene ID

4277

UniProt

Q29980

Conjugation

Unconjugated

Related Pathways

Natural killer cell mediated cytotoxicity

Field of Research

Natural killer cell mediated cytotoxicity

Concentration

1 mg/ml

Dilution

FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.