IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: LBI2A5]
Product Specifications
Background
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
Synonyms
CD25; IDDM10; IL2R; IMD41; p55; TCGFR
Gene Name
Interleukin 2 receptor subunit alpha
Gene ID
3559
UniProt
P01589
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway
Field of Research
Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:1000, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IL2RA
Overview
IL2RA mouse monoclonal antibody, clone LBI2A5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3559
Uniprot URL
https://www.uniprot.org/uniprot/P01589
Curated Selection
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