Nephrin (NPHS1) Mouse Monoclonal Antibody [Clone ID: LBI9D3]
Product Specifications
Background
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
Synonyms
CNF; nephrin; NPHN
Gene Name
NPHS1 nephrin
Gene ID
4868
UniProt
O60500
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:500-1000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NPHS1
Overview
NPHS1 mouse monoclonal antibody, clone LBI9D3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4868
Uniprot URL
https://www.uniprot.org/uniprot/O60500
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