PKR (EIF2AK2) Mouse Monoclonal Antibody [Clone ID: LBI3F5]
Product Specifications
Background
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms
EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR
Gene Name
Eukaryotic translation initiation factor 2 alpha kinase 2
Gene ID
5610
UniProt
P19525
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:500, IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protein Kinase, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
EIF2AK2
Overview
EIF2AK2 mouse monoclonal antibody, clone LBI3F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5610
Uniprot URL
https://www.uniprot.org/uniprot/P19525
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