PKR (EIF2AK2) Mouse Monoclonal Antibody [Clone ID: LBI3F5]

Product Specifications

Background

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Overview

EIF2AK2 mouse monoclonal antibody, clone LBI3F5

Synonyms

EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR

Gene Name

Eukaryotic translation initiation factor 2 alpha kinase 2

Gene ID

5610

UniProt

P19525

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protein Kinase, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.