HLA-DQA2 Mouse Monoclonal Antibody [Clone ID: LBI3E6]
Product Specifications
Background
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells. [provided by RefSeq, Jun 2010]
Synonyms
DC-alpha; DX-ALPHA; HLA-DCA; HLA-DXA; HLADQA2
Gene Name
Major histocompatibility complex, class II, DQ alpha 2
Gene ID
3118
UniProt
P01906
Conjugation
Unconjugated
Related Pathways
Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis
Field of Research
Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, Type I diabetes mellitus, Viral myocarditis
Concentration
1 mg/ml
Dilution
WB 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HLA-DQA2
Overview
HLA-DQA2 mouse monoclonal antibody, clone LBI3E6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3118
Uniprot URL
https://www.uniprot.org/uniprot/P01906
Curated Selection
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