Syntaxin 1a (STX1A) Mouse Monoclonal Antibody [Clone ID: LBI2D11]

Product Specifications

Background

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Overview

STX1A mouse monoclonal antibody, clone LBI2D11

Synonyms

HPC-1; P35-1; STX1; SYN1A

Gene Name

Syntaxin 1A

Gene ID

6804

UniProt

Q16623

Conjugation

Unconjugated

Related Pathways

SNARE interactions in vesicular transport

Field of Research

SNARE interactions in vesicular transport

Concentration

1 mg/ml

Dilution

WB 1:500, IF 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Secreted Protein, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.