Syntaxin 1a (STX1A) Mouse Monoclonal Antibody [Clone ID: LBI2D11]
Product Specifications
Background
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Synonyms
HPC-1; P35-1; STX1; SYN1A
Gene Name
Syntaxin 1A
Gene ID
6804
UniProt
Q16623
Conjugation
Unconjugated
Related Pathways
SNARE interactions in vesicular transport
Field of Research
SNARE interactions in vesicular transport
Concentration
1 mg/ml
Dilution
WB 1:500, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
STX1A
Overview
STX1A mouse monoclonal antibody, clone LBI2D11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6804
Uniprot URL
https://www.uniprot.org/uniprot/Q16623
Curated Selection
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