JAK3 Mouse Monoclonal Antibody [Clone ID: LBI1B4]

Product Specifications

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]

Overview

JAK3 mouse monoclonal antibody, clone LBI1B4

Synonyms

JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK

Gene Name

Janus kinase 3

Gene ID

3718

UniProt

P52333

Conjugation

Unconjugated

Related Pathways

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Field of Research

Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

Concentration

1 mg/ml

Dilution

WB 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protein Kinase

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.