M6PR Mouse Monoclonal Antibody [Clone ID: LBI2F3]
Product Specifications
Background
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. [UniProtKB/Swiss-Prot Function]
Synonyms
CD-M6PR; CD-MPR; MPR-46; MPR 46; MPR46; SMPR
Gene Name
Mannose-6-phosphate receptor, cation dependent
Gene ID
4074
UniProt
P20645
Conjugation
Unconjugated
Related Pathways
Lysosome
Field of Research
Lysosome
Concentration
1 mg/ml
Dilution
WB 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
M6PR
Overview
M6PR mouse monoclonal antibody, clone LBI2F3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4074
Uniprot URL
https://www.uniprot.org/uniprot/P20645
Curated Selection
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