MTHFR Mouse Monoclonal Antibody [Clone ID: LBI2H3]
Product Specifications
Background
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. [provided by RefSeq, Oct 2009]
Synonyms
5,10-methylenetetrahydrofolate reductase (NADPH) ; methylenetetrahydrofolate reductase intermediate form; OTTHUMP00000002367; OTTHUMP00000002368
Gene Name
Methylenetetrahydrofolate reductase (NAD (P) H)
Gene ID
4524
UniProt
P42898
Conjugation
Unconjugated
Related Pathways
Metabolic pathways, Methane metabolism, One carbon pool by folate
Field of Research
Metabolic pathways, Methane metabolism, One carbon pool by folate
Concentration
1 mg/ml
Dilution
WB 1:250~500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MTHFR
Overview
MTHFR mouse monoclonal antibody, clone LBI2H3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4524
Uniprot URL
https://www.uniprot.org/uniprot/P42898
Curated Selection
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