MTHFR Mouse Monoclonal Antibody [Clone ID: LBI2H3]

Product Specifications

Background

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. [provided by RefSeq, Oct 2009]

Overview

MTHFR mouse monoclonal antibody, clone LBI2H3

Synonyms

5,10-methylenetetrahydrofolate reductase (NADPH) ; methylenetetrahydrofolate reductase intermediate form; OTTHUMP00000002367; OTTHUMP00000002368

Gene Name

Methylenetetrahydrofolate reductase (NAD (P) H)

Gene ID

4524

UniProt

P42898

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Methane metabolism, One carbon pool by folate

Field of Research

Metabolic pathways, Methane metabolism, One carbon pool by folate

Concentration

1 mg/ml

Dilution

WB 1:250~500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.