IL28 Receptor alpha (IFNLR1) Mouse Monoclonal Antibody [Clone ID: LBI3F5]
Product Specifications
Background
The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms
CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2
Gene Name
Interferon lambda receptor 1
Gene ID
163702
UniProt
Q8IU57
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Field of Research
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:500, IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IFNLR1
Overview
IFNLR1 mouse monoclonal antibody, clone LBI3F5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=163702
Uniprot URL
https://www.uniprot.org/uniprot/Q8IU57
Curated Selection
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