HB EGF (HBEGF) Mouse Monoclonal Antibody [Clone ID: LBI6F4]
Product Specifications
Background
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]
Overview
HBEGF mouse monoclonal antibody, clone LBI6F4
Synonyms
DTR; DTS; DTSF; HEGFL
Gene Name
Heparin binding EGF like growth factor
Gene ID
1839
UniProt
Q99075
Conjugation
Unconjugated
Related Pathways
Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway
Field of Research
Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HBEGF
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1839
Uniprot URL
https://www.uniprot.org/uniprot/Q99075
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