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Gamma Catenin (JUP) Mouse Monoclonal Antibody [Clone ID: LBI4D5]

Product Specifications

Background

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]

Synonyms

CTNNG; DP3; DPIII; PDGB; PG; PKGB

Gene Name

Junction plakoglobin

Gene ID

3728

UniProt

P14923

Conjugation

Unconjugated

Related Pathways

Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer

Field of Research

Acute myeloid leukemia, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Pathways in cancer

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

JUP

Overview

JUP mouse monoclonal antibody, clone LBI4D5

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3728

Uniprot URL

https://www.uniprot.org/uniprot/P14923

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