TNFRSF4 Mouse Monoclonal Antibody [Clone ID: LBI2F12A2]

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

Overview

TNFRSF4 mouse monoclonal antibody, clone LBI2F12A2

Synonyms

ACT35; CD134; IMD16; OX40; TXGP1L

Gene Name

Tumor necrosis factor receptor superfamily member 4

Gene ID

7293

UniProt

P43489

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Concentration

1 mg/ml

Dilution

WB 1:500, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.