TNFRSF4 Mouse Monoclonal Antibody [Clone ID: LBI2F12A2]
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Synonyms
ACT35; CD134; IMD16; OX40; TXGP1L
Gene Name
Tumor necrosis factor receptor superfamily member 4
Gene ID
7293
UniProt
P43489
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
1 mg/ml
Dilution
WB 1:500, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNFRSF4
Overview
TNFRSF4 mouse monoclonal antibody, clone LBI2F12A2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7293
Uniprot URL
https://www.uniprot.org/uniprot/P43489
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