IL15RA Mouse Monoclonal Antibody [Clone ID: LBI6B2]

Product Specifications

Background

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Apr 2010]

Overview

IL15RA mouse monoclonal antibody, clone LBI6B2

Synonyms

CD215

Gene Name

Interleukin 15 receptor subunit alpha

Gene ID

3601

UniProt

Q13261

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Secreted Protein

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.