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BMP6 Mouse Monoclonal Antibody [Clone ID: LBI1B11]

Product Specifications

Background

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

Synonyms

VGR; VGR1

Gene Name

Bone morphogenetic protein 6

Gene ID

654

UniProt

P22004

Conjugation

Unconjugated

Related Pathways

Hedgehog signaling pathway, TGF-beta signaling pathway

Field of Research

Hedgehog signaling pathway, TGF-beta signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

BMP6

Overview

BMP6 mouse monoclonal antibody, clone LBI1B11

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=654

Uniprot URL

https://www.uniprot.org/uniprot/P22004

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