CRMP2 (DPYSL2) Mouse Monoclonal Antibody [Clone ID: LBI5D7]
Product Specifications
Background
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Synonyms
CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2
Gene Name
Dihydropyrimidinase like 2
Gene ID
1808
UniProt
Q16555
Conjugation
Unconjugated
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
1 mg/ml
Dilution
WB 1:500~2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
DPYSL2
Overview
DPYSL2 mouse monoclonal antibody, clone LBI5D7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1808
Uniprot URL
https://www.uniprot.org/uniprot/Q16555
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