SIRT-IN-3
Product Specifications
UNSPSC Description
SIRT-IN-3 is a potent SIRT inhibitor, with an IC50 of 17 μM for SIRT1. SIRT-IN-3 shows about 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3, respectively (IC50 of 74 μM and 235 μM for SIRT2 and SIRT3, respectively)[1].
Target Antigen
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sirt-in-3.html
Smiles
O=C(N)C1=CC=CC=C1NC2=CC=CC=C2
Molecular Weight
212.25
References & Citations
[1]Suzuki T, et al. 2-Anilinobenzamides as SIRT inhibitors. ChemMedChem. 2006 Oct;1(10):1059-62.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-133998/SIRT-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133998/SIRT-IN-3-SDS-MedChemExpress.pdf
CAS Number
1211-19-4
Available Sizes
Curated Selection
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