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IKB epsilon (NFKBIE) Mouse Monoclonal Antibody [Clone ID: LBI4F7]

Product Specifications

Background

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011]

Synonyms

IKBE

Gene Name

NFKB inhibitor epsilon

Gene ID

4794

UniProt

O00221

Conjugation

Unconjugated

Related Pathways

Adipocytokine signaling pathway, B cell receptor signaling pathway, Neurotrophin signaling pathway, T cell receptor signaling pathway

Field of Research

Adipocytokine signaling pathway, B cell receptor signaling pathway, Neurotrophin signaling pathway, T cell receptor signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:500~2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

NFKBIE

Overview

NFKBIE mouse monoclonal antibody, clone LBI4F7

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=4794

Uniprot URL

https://www.uniprot.org/uniprot/O00221

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