RUNX3 Mouse Monoclonal Antibody [Clone ID: LBI2G1]

Product Specifications

Background

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

RUNX3 mouse monoclonal antibody, clone LBI2G1

Synonyms

AML2; CBFA3; PEBP2aC

Gene Name

Runt related transcription factor 3

Gene ID

864

UniProt

Q13761

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.