IQGAP1 Mouse Monoclonal Antibody [Clone ID: LBI7F5]

Product Specifications

Background

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

Overview

IQGAP1 mouse monoclonal antibody, clone LBI7F5

Synonyms

HUMORFA01; p195; SAR1

Gene Name

IQ motif containing GTPase activating protein 1

Gene ID

8826

UniProt

P46940

Conjugation

Unconjugated

Related Pathways

Adherens junction, Regulation of actin cytoskeleton

Field of Research

Adherens junction, Regulation of actin cytoskeleton

Concentration

1 mg/ml

Dilution

WB 1:500~2000, IHC 1:5000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.