Cryptochrome I (CRY1) Mouse Monoclonal Antibody [Clone ID: LBI2C10]
Product Specifications
Background
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
Synonyms
PHLL1
Gene Name
Cryptochrome circadian clock 1
Gene ID
1407
UniProt
Q16526
Conjugation
Unconjugated
Related Pathways
Circadian rhythm - mammal
Field of Research
Circadian rhythm - mammal
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CRY1
Overview
CRY1 mouse monoclonal antibody, clone LBI2C10
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1407
Uniprot URL
https://www.uniprot.org/uniprot/Q16526
Curated Selection
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