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Myotilin (MYOT) Mouse Monoclonal Antibody [Clone ID: LBI5E11]

Product Specifications

Background

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]

Synonyms

LGMD1; LGMD1A; MFM3; TTID; TTOD

Gene Name

Myotilin

Gene ID

9499

UniProt

Q9UBF9

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:1000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

MYOT

Overview

MYOT mouse monoclonal antibody, clone LBI5E11

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9499

Uniprot URL

https://www.uniprot.org/uniprot/Q9UBF9

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