OTX2 Mouse Monoclonal Antibody [Clone ID: LBI2B3]
Product Specifications
Background
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6) . This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
Synonyms
CPHD6; MCOPS5
Gene Name
Orthodenticle homeobox 2
Gene ID
5015
UniProt
P32243
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
OTX2
Overview
OTX2 mouse monoclonal antibody, clone LBI2B3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5015
Uniprot URL
https://www.uniprot.org/uniprot/P32243
Curated Selection
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