IRF3 Mouse Monoclonal Antibody [Clone ID: LBI2G6]
Product Specifications
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Synonyms
IIAE7
Gene Name
Interferon regulatory factor 3
Gene ID
3661
UniProt
Q14653
Conjugation
Unconjugated
Related Pathways
Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Field of Research
Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IRF3
Overview
IRF3 mouse monoclonal antibody, clone LBI2G6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3661
Uniprot URL
https://www.uniprot.org/uniprot/Q14653
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