BNP (NPPB) Mouse Monoclonal Antibody [Clone ID: LBI6F8]
Product Specifications
Background
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Jul 2008]
Synonyms
BNP; Iso-ANP
Gene Name
Natriuretic peptide B
Gene ID
4879
UniProt
P16860
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein, Stem cell - Pluripotency
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NPPB
Overview
NPPB mouse monoclonal antibody, clone LBI6F8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4879
Uniprot URL
https://www.uniprot.org/uniprot/P16860
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