Gemin 2 (GEMIN2) Mouse Monoclonal Antibody [Clone ID: LBI4A2]
Product Specifications
Background
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
Synonyms
SIP1; SIP1-delta
Gene Name
Gem nuclear organelle associated protein 2
Gene ID
8487
UniProt
O14893
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
GEMIN2
Overview
SIP1 mouse monoclonal antibody, clone LBI4A2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8487
Uniprot URL
https://www.uniprot.org/uniprot/O14893
Curated Selection
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