SHMT2 Mouse Monoclonal Antibody [Clone ID: LBI1E12]
Product Specifications
Background
This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Synonyms
GLYA; HEL-S-51e; NEDCASB; SHMT
Gene Name
Serine hydroxymethyltransferase 2
Gene ID
6472
UniProt
P34897
Conjugation
Unconjugated
Related Pathways
Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Methane metabolism, One carbon pool by folate
Field of Research
Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Methane metabolism, One carbon pool by folate
Concentration
1 mg/ml
Dilution
WB 1:500~2000, IHC 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SHMT2
Overview
SHMT2 mouse monoclonal antibody, clone LBI1E12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6472
Uniprot URL
https://www.uniprot.org/uniprot/P34897
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