ICOS Ligand (ICOSLG) Mouse Monoclonal Antibody [Clone ID: LBI2C5]
Product Specifications
Background
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. [UniProtKB/Swiss-Prot Function]
Overview
ICOSLG mouse monoclonal antibody, clone LBI2C5
Synonyms
B7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS
Gene Name
Inducible T-cell costimulator ligand
Gene ID
23308
UniProt
O75144
Conjugation
Unconjugated
Related Pathways
Cell adhesion molecules (CAMs)
Field of Research
Cell adhesion molecules (CAMs)
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ICOSLG
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23308
Uniprot URL
https://www.uniprot.org/uniprot/O75144
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