EGLN2 Mouse Monoclonal Antibody [Clone ID: LBI5E11]

Product Specifications

Background

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]

Overview

EGLN2 mouse monoclonal antibody, clone LBI5E11

Synonyms

EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1

Gene Name

Egl-9 family hypoxia inducible factor 2

Gene ID

112398

UniProt

Q96KS0

Conjugation

Unconjugated

Related Pathways

Pathways in cancer, Renal cell carcinoma

Field of Research

Pathways in cancer, Renal cell carcinoma

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.