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ICOS Ligand (ICOSLG) Mouse Monoclonal Antibody [Clone ID: LBI1B8]

Product Specifications

Background

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. [UniProtKB/Swiss-Prot Function]

Synonyms

B7-H2; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS

Gene Name

Inducible T-cell costimulator ligand

Gene ID

23308

UniProt

O75144

Conjugation

Unconjugated

Related Pathways

Cell adhesion molecules (CAMs)

Field of Research

Cell adhesion molecules (CAMs)

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

ICOSLG

Overview

ICOSLG mouse monoclonal antibody, clone LBI1B8

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=23308

Uniprot URL

https://www.uniprot.org/uniprot/O75144

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